Peptic ulcer candidate genes

نویسندگان

چکیده

Hereditary predisposition is one of the aetiopathogenetic factors in development gastric ulcer and duodenal ulcer. The analysis literature materials allows us to identify a number candidate genes that play role formation peptic ulcer: PSCA, ABO, IL1β, IL1RN, TNFα, HSP70-1, GSR, TLR4, TLR2, TLR9, MMP-1, MMP-3, MMP- 9, TIMP-3, PGC, MIF, MPO, COX-1. Considering most studies were carried out abroad, results differ depending on ethnic characteristics studied groups, sometimes they are contradictory, works domestic scientists this problem rare, further study polymorphic variants necessary.

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ژورنال

عنوان ژورنال: Experimental & clinical gastroenterology

سال: 2021

ISSN: ['1682-8658']

DOI: https://doi.org/10.31146/1682-8658-ecg-186-2-52-57